St. Louis – Missouri’s Gateway to Prosperity

St. Louis was founded, designed and built more than 250 years ago to serve as the centerpiece of a vast inland empire – a feat early St. Louisans surpassed. The city developed quickly and became the “gateway” to western American expansion.


St. Louis today is an exciting metropolitan region with 2.9 million people, 14 Fortune 1000 companies and some of the largest private firms in the U.S. Among those industry leaders that maintain significant operations in St. Louis are Ameren, Anhueser-Busch In-Bev, AT&T, Boeing, BJC Healthcare, Centene, Edward Jones, Emerson, Enterprise, Express Scripts, General Motors, Maritz, MasterCard, Bayer, Olin, Peabody Energy, Millipore Sigma and Wells Fargo Advisors.

St. Louis is also home to numerous small and mid-sized companies that find the region’s know-your-neighbors Midwest vibe refreshingly supportive. Perhaps that’s why Popular Mechanics Magazine named St. Louis one of the nation’s best places to
start a business.

With a central location, infrastructure capacity, favorable cost structure and high-quality cultural and educational institutions, St. Louis’ $150 billion regional economy is broad and growing.

The 15-county region comprises hundreds of historic and diverse neighborhoods as well as dozens of world-class cultural and entertainment attractions. Historic. Progressive. Diverse. St. Louis is an important national, economic and social asset.

St. Louis is Missouri’s gateway to prosperity.