Keith J. Stine, Chair
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Professor Chickos has been a member of the UMSL faculty since 1969. He received his undergraduate degree from the State University of New York-Buffalo, and his Ph.D. from Cornell University. He was an NIH Postdoctoral Fellow at Princeton University and the University of Wisconsin.
All scientific endeavors are dependent on the availability of reliable thermodynamic and physical property data. These data form the foundations on which our current understanding of the physical world is based. The measurement and collection of such data are a fundamental scientific task, common to all who practice the discipline.
We have had an interest in developing simple algorithms to model some of these physical properties. The purpose for doing so is to provide data in the absence of experiment and to provide a basis for the selection of a particular measurement in the presence of two or more discordant values. In addition, the process of distilling these physical data using these algorithms can sometimes produce parameters that can be used to evaluate molecular properties that cannot be measured directly.
Simple models have been developed to estimate condensed phase properties such as vaporization enthalpies, heat capacities, fusion entropies and enthalpies, vapor pressures and sublimation enthalpies of small molecules. Recently, the parameters generated by these algorithms have also been used in estimating fusion enthalpies of polymers and conformational entropy changes in globular proteins.
The development of models to mimic physical properties requires extensive databases and a constant updating of these databases. As a result, we have developed a collaborative interaction with the National Institutes of Standards and Technology in Washington DC in which physical property data flow freely in both directions. We currently supply NIST with sublimation enthalpies of organic compounds.
Coupled with our interest to develop models for such properties is the need to obtain experimental data. A variety of physical properties are measured in our research laboratories that include measurements of vaporization, sublimation and fusion enthalpies. We are also examining new simpler methods of making these measurements. One such process recently developed, correlation gas chromatography, affords the vaporization enthalpy of a solid or liquids at 298 K by simply using retention time measurements of knowns and unknowns.
″The vapor pressure and vaporization enthalpy of (-) β-Elemene and (-) β-Bisabolene by correlation gas chromatography″, D. Barton and J. S. Chickos, J. Chem. Thermodyn. 2020, 148, 105139t.
″The vapor pressure and vaporization enthalpy of pristane and phytane by correlation gas chromatography″, C. Fischer-Lodike, A. Zafar and J. S. Chickos, J. Chem. Thermodyn. 2020, 141, 105931.
″ Vapor pressure and vaporization enthalpy studies of the major components of ginger, α-zingiberene, β-sesquiphellandrene and (-) ar curcumene by correlation gas chromatography″, N. Siripoltangman and J. S. Chickos, J. Chem. Thermodyn. 2019, 138, 107
″Sublimation Enthalpies of Organic Compounds: A Very Large Database with a Match to Crystal Structure Determinations and a Comparison with Lattice Energies ″ J. S. Chickos and A. Gavezzotti, Crystal Growth & Design, 2019, 11, 6566
″The vapor pressure and vaporization enthalpy of squalene and squalane by correlation gas chromatography,″ A. Zafar and J. S. Chickos, J. Chem. Thermodyn. 2019, 135, 192
″Vapor pressure and vaporization enthalpy studies of (+)-longifolene, (-)-isolongifolene and β-myrcene by correlation gas chromatography,″ P. Umnahanant, A, Zafar, V. Kankala and J. S. Chickos, J. Chem. Thermodyn. 2019, 131, 583.
″Vaporization enthalpy and vapor pressure of (-) Ambroxide and Galaxolide by correlation gas chromatography,″ K. Wootitunthipong and J. S. Chickos, J. Chem. Thermodyn. 2019, 129, 121
″Thermochemical properties of sesquiterpenes in natural products by correlation gas chromatography: Application to bergamotene oil,″ M. Orf, M. Kurian, L. Espinosa, C. Nelson, D. Simmons and J. S. Chickos, J. Chem. Thermodyn. 2018, 126, 128
″The vaporization enthalpy and vapor pressures of liquid adamantane, diamantane and α- and β-cedrene by correlation gas chromatography,″ C. Nelson, Carissa and J. S. Chickos, J. Chem. Thermodyn. 2018, 121, 175
″Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds and Ionic Liquids. Sublimation, Vaporization, and Fusion Enthalpies from 1880 to 2015. Part 2. C11-C192,″ W. Acree and J. S. Chickos, J. Phys. Chem. Ref. Data, 2017, 46, 013104.
″Evaluation of vaporization enthalpies and liquid vapor pressures of cedrol, nerolidol, and 1-adamantanol by correlation gas chromatography,″ C. R. Nelson and J. S. Chickos, J. Chem. Thermodyn. 2017, 115, 253.
″Vapor pressures and vaporization enthalpy of (-) α-bisabolol and (dl) menthol by correlation gas chromatography,″ L. Keating, H. H. Harris and J. S. Chickos, J. Chem. Thermodyn. 2017, 107, 18.
″Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds. Sublimation, Vaporization and Fusion Enthalpies From 1880 to 2015,. Part 1. C1 - C10,″ W. Acree and J. S. Chickos, J. Phys. Chem. Ref. Data, 2016, 45, 033101
The vapor pressure and vaporization enthalpy of R-(+)-menthofuran, a hepatotoxin metabolically derived from the abortifacient terpene, (R)-(+)-pulegone by correlation gas chromatography,″ C. Gobble and J. S. Chickos, J. Chem. Thermodynam. 2016, 98,135
″Vaporization Enthalpies and Vapor Pressures of Some Insect Pheromones by Correlation Gas Chromatography,″ S. Goodrich, J. Hasanovic, C. Gobble and J. S. Chickos, J. Chem. Eng. Data 2016, 61, 1524.