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Nigam P. Rath

Nigam P. Rath

Dr. Rath received B.Sc. (Hons.) and M.Sc. degrees from Berhampur University in India, and a Ph.D. from Oklahoma State University. He was a Postdoctoral Fellow and Assistant Faculty Fellow at the University of Notre Dame prior to joining the UMSL faculty as Research Assistant Professor in 1989. He was promoted to Research Associate Professor in 1996 and Research Professor in 2004.
Office: N304
Phone: (314)516-5333
Fax: (314)516-5342

Research Interests

Dr. Rath's research interests involve the use of single crystal X-ray diffraction techniques for three dimensional solid state-molecular and crystal structure determination of novel organic and organometallic compounds. Currently, Dr. Rath is the Director of the X-ray Diffraction Laboratory of the Department of Chemistry and Biochemistry and the Center for Nanoscience. Current research interests include study of weak interactions in the solid state, polymorphism, structure solution and refinement of twin structures and development of techniques and instrumentation for accurate data collection for small molecules.

Selected Publications

″Glycosyl nitrates in synthesis: streamlined access to glucopyranose building blocks differentiated at C-2,″ T. Wang, S. S. J. P. Yasomanee, N. P. Rath, Nigam K. J. Stine and A. V. Demchenko, Org. & Biomol. Chem. 2018, 16, 3596

″Stream-lined synthesis of 3-hydroxy-β-lactams: Norrish-Yang type II photocyclizations of β-ketoformamides,″ J. L. Markley, T. L. Morse, N. P. Rath and T. A, Wencewicz, Tetrahedron, 2018, 74, 2743

″Electronic versus steric effects of pyridinophane ligands on Pd(III) complexes,″ F. Tang, S V. Park, N. P. Rath and L. M. Mirica, Dalton Trans. 2018, 47, 1151

″New cationic and neutral copper(II) complexes containing 7-hydroxy-4-oxo-4[H]-chromene derived ONO pincer ligands: Synthesis, characterization and in vitro biological evaluations,″ G. Kalaiarasi, S. R. Jeya Rajkumar, S. Dharani, N. P. Rath and R. Prabhakaran, J. Photochem. Photobiol. B, 2018, 180, 77

″Cationic ruthenium complex of the formula [RuCl(2,6-diacetylpyridine)(PPh3)2]BArF and its catalytic activity in the formation of enol esters,″ M. J. Stark, D. T. Tang, N. P. Rath and E. B. Bauer, Tet. Lett. 2018, 59, 873

″Stream-lined synthesis of 3-hydroxy-β-lactams: Norrish-Yang type II photocyclizations of β-ketoformamides,″ J. L. Markley, T. L. Morse, N. P. Rath and T. A. Wencewicz, Tetrahedron 2018, 74, 2743

″A Practical Gram-Scale Synthesis of Acrylohydroxamic Acid,″ B. C. Hamper, B. T. Sullivan, N. P. Rath and C. D. Spilling, Synthesis2017, 49, 5335

″Cadmium Bis(phenyldithiocarbamate) as a Nanocrystal Shell-Growth Precursor,″ C. E. Morrison, F. Wang, N. P. Rath, B. M Wieliczka, R. A. Loomis and W. H. Buhro, Inorg. Chem. 2017, 56, 12920

″cis-1,2-Bis(diphenylphosphino)ethylene copper(I) catalyzed C-H activation and carboxylation of terminal alkynes,″ M. Trivedi, J. R. Smreker, G. Singh, A. Kumar and N. P. Rath, New. J. Chem. 2017, 41, 14145.

″Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer's Disease,″ A. K. Sharma, J. W. Schultz, J. T. Prior, N. P. Rath and L. M. Mirica, Inorg. Chem. 2017, 56, 13801

″Synthesis, structural characterization and catalytic activity of indenyl complexes of ruthenium bearing fluorinated phosphine ligands,″ M. J. Stark, M. J. Shaw, A. Fadamin, N. P. Rath and E. B. Bauer, J. Organomet. Chem. 2017, 847, 41.

″Extending the S-benzimidazolyl (SBiz) platform: N-alkylated SBiz glycosyl donors with the universal activation profile,″  S. J. Hasty, N. P. Rath and A. V. Demchenko, Pure Appl. Chem. 2017, 89, 1321

67Ga-metalloprobes: monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cells,″ J. Sivapackiam, S. E. Harpstrite, N. P. Rath and V. Sharma, Vijay, MedChemComm. 2017, 8, 158.

″Oxidative C-C Bond Formation Reactivity of Organometallic Ni(II), Ni(III), and Ni(IV) Complexes,″  M. B. Watson, N. P. Rath and L. M. Mirica, J. Am. Chem. Soc. 2017, 139, 35

″S-Benzimidazolyl (SBiz) Imidates as a Platform for Oligosaccharide Synthesis via Active-Latent, Armed-Disarmed, Selective, and Orthogonal Activations,″ S. J. Hasty, M. D. Bandara, N. P. Rath and A. V. Demchenko, J. Org. Chem. 2017, 82, 1904.