Demchenko pic 2016

Professor Demchenko received his M. Sc. in Chemical Engineering from the D. I. Mendeleyev University of Chemical Technology of Russia, Moscow (1988) and  his Ph. D. in Organic Chemistry from the N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow (1993). He was a post-doctoral fellow at the University of Birmingham, (UK) and a research assistant at the Complex Carbohydrate Research Center at the University of Georgia before joining the UMSL faculty in 2001. He was appointed Curators' Professor of Chemistry and Biochemistry in 2014.

demchenkoa@umsl.edu Fax: (314) 516-5342
Office: B434
Tel: (314) 516-7995 Glycoworld (Alexei Demchenko Laboratory Homepage)

Research Interests

Figure 2

Selected Publications

″OFox imidates as versatile glycosyl donors for chemical glycosylation,″ S. S. Nigudkar, T. Wang, S. G. Pistorio, J. P. Yasomanee, K. J. Stine and A. V. Demchenko, Org. & Biomol. Chem. 2017, 15, 348.

″Conformationally super-armed S-ethyl glycosyl donors as effective building blocks for chemoselective oligosaccharide synthesis in one pot,″ M. D. Bandara, J. P. Yasomanee, N. P. Rath, C. M. Pedersen, M. Bols and A. V. Demchenko, Org. & Biomol. Chem, 2016, Ahead of Print″

Templated Oligosaccharide Synthesis: Driving Forces and Mechanistic Aspects,″ X. G. Ziao, P. Pornsuriyasak and A. V. Demchenko, J. Org. Chem. 2016, 81, 12232.

″The synthesis of the repeating unit of capsular polysaccharide Staphylococcus aureus type 5 to study chemical activation and conjugation of native CP5,″ J. P. Yasomanee, S. Visansirikul, P. Pornsuriyasak, M. Thompson, S. A. Kolodziej and A. V. Demchenko, J. Org. Chem. 2016, 81, 5981.

″Templated Oligosaccharide Synthesis: The Linker Effect on the Stereoselectivity of Glycosylation,″ P. Pornsuriyasak, Papapida; X. G. Jia, S. Kaeothip and A. V. Demchenko, Org. Lett. 2016, 18, 2316.

″2,3-Di-O-picolinyl building blocks as glycosyl donors with switchable stereoselectivity,″ J. P. Yasomanee, A. R. Parameswar, P. Pornsuriyasak, N. P. Rath and A. V. Demchenko, Org. & Biomol. Chem. 2016, 14, 3159.

″Electrochemical impedance spectroscopy study of carbohydrate-terminated alkanethiol monolayers on nanoporous gold: Implications for pore wetting,″ A. Sharma, J. K. Bhattarai, S. S. Nigudkar, S. G. Pistorio, A. V. Demchenko and K. J. Stine, J. Electroanal. Chem. 2016, 782, 174

″Electrochemical impedance spectroscopy study of Concanavalin A binding to self-assembled monolayers of mannosides on gold wire electrodes,″ J. K. Bhattarai, Y. H. Tan, B, Pandey, K. Fujikawa, A. V. Demchenko and K. J. Stine, J. Electroanal. Chem. 2016, 780, 311

″HPLC-Assisted Automated Oligosaccharide Synthesis: Implementation of the Autosampler as a Mode of the Reagent Delivery,″ S. G. Pistorio, S. S. Nigudkar, K. J. Stine, Keith and A. V. Demchenko, J. Org. Chem. 2016, 81, 8796

″One-pot synthesis and benzylation of galactose, glucose, and mannose 1,2-orthoesters″ X. G. Jia, A. K. Kayastha, S. J. Hasty, Juan A. Ventura and A. V. Demchenko, Carbohydrate Chemistry: Proven Synthetic Methods 2015, 3, 203.

″A Concise Synthesis of the Repeating Unit of Capsular Polysaccharide Staphylococcus aureus Type 8″, S. Visansirikul, J. Yasomanee, P. Pornsuriyasak, M. N. Kamat, N. M. Podvalnyy, C. P. Gobble, M. Thompson, S. A. Kolodziej and A. V. Demchenko, Org Lett. 2015, 17, 2382.

“Hydrogen-Bonded Mediated Aglycone Delivery (HAD): A highly Stereoselective Synthesis of 1,2-cis-a-D-Glucosides from Common Glycoside Donors”’ J. Yasomanee and A. V.  Demchenko, Chem.  A Eur. J. 2015, 21, 6572. 

“Electrochemical annealing of nanoporous gold by application of cyclic potential sweeps”, A. Sharma, J. K. Bhattarai, A. J.  Alla, A. V.  Demchenko and K. J. Stine, Nanotechnology 2015, 26, 85602. 

 “Stereocontrolled 1,2-cis glycosylation as the driving force of progress in synthetic carbohydrate chemistry”, S. Nigudkar and A. V. Demchenko, Chem. Science 2015, 6, 2687 

"Electrochemical Synthesis of Nanostructured Gold Film for the Study of Carbohydrate-Lectin Interactions Using Localized Surface Plasmon Resonance Spectroscopy”, J. K. Bhattarai, A. Sharma,  K. Fujikawa, Al. V. Demchenko, and K. J. Stine, Carbohydrate Res, 2015,405, 55

"Hydrogen bond mediated aglycone delivery: Synthesis of linear and branched α-glucans″, J. P. Yasomanee and A. V. Demchenko, Angew Chem. Intl Ed. 2014, 3, 10453.