The UM-St Louis High Resolution NMR Facility is located in the Department of Chemistry and Biochemistry on the second floor of Benton Hall (B210) and houses three NMR spectrometers: a Bruker ARX-500, a Bruker Avance 300 and a Varian Unity Plus 300. While these instruments are primarily for the use of the faculty, postdoctoral, and students in the Department of Chemistry and Biochemistry, other users (corporate other universities, and organizations) are welcome. The facility staff will provide NMR services as needed. For more information please contact to Dr. Rensheng Luo at (314) 516-5330.
Bruker ARX 500 MHz NMR
The Bruker ARX-500 spectrometer is operated by a Silicon Graphics INDY R5000 workstation. It has two probes: a 5 mm broadband and a 5 mm inverse gradient broadband, each of which is capable of variable temperature experiments (-150 to + 200 oC for liquids). The Bruker ARX-500 spectrometer is a research-oriented instrument. It is equipped with dual radiofrequency channels and used for molecules requiring better peak resolution, (complex) structure elucidation and variable temperature analyses on a wide range of organic, organometallic, inorganic, and biochemical systems, as well as natural products and host-guest systems. Experiments that are typically performed include 2D COSY, NOESY, ROESY, TOCSY, HSQC, HMQC, HMBC and selective excitation.
Bruker Avance 300MHz NMR
The Avance 300 spectrometer is currently equipped with a four-nucleus probe (1H, 13C, 19F, and 31P) with z-gradients. An additional 5 mm switchable broadband probe tunable for 1H-19F/15N -31P is also available. This instrument is used primarily for routine walk-in use for monitoring reactions and checking the purity of samples, but it is also used for longer run experiments such as 1D 13C and routine 2D experiments: HMQC, HSQC, and HMBC in the evening and weekends.
Varian Unity Plus 300 MHz NMRThe Varian Unity Plus 300 is equipped with a wide bore Oxford superconducting magnet to accommodate probes for running solid state NMR experiments. It has two radiofrequency channels and is capable of broadband detection. This instrument is used primarily for detection of heteronuclei such as 11B, 13C, 31P, 119Sn, and 195Pt, experiments that require long detection time. It has four probes: two 5mm switchable broadband probes with boron-free glass insert, a 5mm switchable inverse broadband probe, and a 7mm magic angle probe for CP-MAS experiments.