/* the following lines are all needed in multicntrl.dat ... do not add or delete lines but change entry on left of each line as you see fit ... */ finaltree 2 ... number of genes ... FOLLOWING LINES CONTAIN ONLY NAMES OF DATA FILES oest.gene1 oest.gene2 10000 ... numsamps: How many times should the Markov chain be sampled? 1000 ... sampfreq: How many cycles between samples of the Markov chain? 1000000 ... burnin: How many cycles before the first sample of Markov chain? 1.2 ... rttm: a priori expected number of time units between tip and root 0.01 ... rttmsd: standard deviation of prior for time between tip and root 0.1643172 ... rtrate: mean of prior distribution for rate at root node 0.1643172 ... rtratesd: standard deviation of prior for rate at root node 1 ... brownmean: mean of prior for brownian motion constant "nu" 1 ... brownsd: std. deviation of prior for brownian motion constant "nu" /* the following lines are all needed (i.e., do not delete them) but you may not want to alter entries unless you are familiar with the computer code */ 1.0 ... minab: parameter for beta prior on proportional node depth 0.1 ... newk: parameter in Markov chain proposal step 0.5 ... othk: parameter in Markov chain proposal step 0.5 ... thek: parameter in Markov chain proposal step 10.0 ... bigtime: number higher than time units between tip and root could be in your wildest imagination /* the program will expect the entry below to be the number of constraints and then the specified number of constraints should follow on subsequent lines Use L for the age as the lower boundary for the node age (must be older than) Use U for the age being the upper boundary (must be younger than)*/ 5 ... number of constraints on node times L 31 0.4 L 49 0.54 L 50 0.78 L 51 1.08 L 52 1.19 0 ... number of tips which are not collected at time 0 0 ... nodata: 1 means approximate prior, 0 means approximate posterior 0 ...commonbrown: 1 if all genes have same tendency to change rate, 0 otherwise