University of Missouri - Saint Louis
The Graduate School
An oral examination in defense of the dissertation for the degree
Doctor of Philosophy in Chemistry
Sneha C. Ranade
M.S. in Chemistry, August 2009, University of Missouri-St. Louis
M.Sc. in Chemistry, June 2006, University of Mumbai
B.Sc. in Chemistry, June 2004, University of Mumbai
Glycosyl Thiocarbamates As New Building Blocks for Chemical Glycosylation
Having multiple functions in biological systems, e.g. fertilization, blood group determination, growth; carbohydrates have remained attractive subjects for study. They are also involved in various life threatening biological processes, such as viral and bacterial infections, tumor growth etc. Understanding of these involvements/interactions of carbohydrates in such critical processes is essential for the development of carbohydrate based vaccines and therapeutics. Although carbohydrates are present abundantly in nature, their isolation is pretty cumbersome and low yielding, which is why the synthesis of carbohydrate units has been of interest to many scientists. Efforts have been made to make these synthetic methods more and more efficient, with the primary focus on the yield and stereoselectivity of glycosylation reactions.
|Date: November 13, 2012||
Time: 10:00 a.m. to 12.00 p.m.
Place: 451 Benton Hall
Alexei Demchenko, Ph.D.(Advisor)
|Rudolf E. K. Winter, Ph.D.|
|Keith Stine, Ph.D.||Eike Bauer, Ph.D.|