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 The
Neuropsychology and Applied Neuroimaging Laboratory (NAN) is largely
focused on understanding the contribution of subcortical brain systems
to cognitive and affective behavior. Our lab focuses on two conditions
that provide opportunities to study subcortical brain systems, including
subcortical ischemic vascular disease (SIVD) associated with advanced
age, and human immunodeficiency virus (HIV). The neuropathology of SIVD
and HIV predominately involves both white matter and subcortical gray
matter structures. Our research studies typically incorporate
neuropsychological tests to examine behavioral indices of brain
function. These tests are weighted towards domains of function subserved
by subcortical brain systems (e.g., information processing speed). The
NAN research program at UMSL incorporates structural neuroimaging,
diffusion tensor imaging, and functional neuroimaging to explore the
neuronal integrity of brain systems. The neuroimaging aspects of our
research program are conducted in collaboration with co-investigators
based at Washington University School of Medicine, Brown Medical School,
Harvard Medical School, and the University of Sydney.
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