Nigam P. Rath
Dr. Rath received B.Sc. (Hons.) and M.Sc. degrees from Berhampur
University in India, and a Ph.D. from Oklahoma State University.
He was a Postdoctoral Fellow and Assistant Faculty Fellow at
the University of Notre Dame prior to joining the UM-St. Louis
faculty as Research Assistant Professor in 1989. He was promoted
to Research Associate Professor in 1996 and Research Professor
in 2004.
nigam_rath@umsl.edu
Office: N304
Phone: (314) 516-5333
Fax: (314) 516-5342
Research
Interests
Dr. Rath's research interests involve the use of single
crystal X-ray diffraction techniques for three dimensional solid state-molecular
and crystal structure determination of novel organic and organometallic
compounds. Currently, Dr. Rath is the Director of the X-ray Diffraction
Laboratory of the Department
of Chemistry and Biochemistry and the Center for Nanoscience.
Current research interests include study of weak interactions in the
solid state, polymorphism, structure solution and refinement of twin
structures and development of techniques and instrumentation for accurate
data collection for small molecules.
Selected Publications
"Ligand substitution within nonporous crystals of a coordination polymer: elimination from and insertion into Ag-O bonds by alcohol molecules in a solid-vapor reaction", S. Libri, M. Mahler, G. M. Espallargas, D. C. N. G. Singh, J. Soleimannejad, H. Adams, M. D. Burgard, N. P. Rath, M. Brunelli and Lee Brammer Angewandte Chemie, International Edition, 2008, 47, 1693.
"Molecular Packing and Solid-State Fluorescence of Alkoxy-Cyano Substituted Diphenylbutadienes: Structure of the Luminescent Aggregates", R. Davis, N. S. Kumar, A. Saleesh; S. C. H. Shibu; N. P. Rath, N. Tamaoki and S. Das, Journal of Physical Chemistry C, 2008, 112, 2137.
"Synthesis, Characterization, and Reactivity of Iron Trisamidoamine Complexes That Undergo Both Metal- and Ligand-Centered Oxidative Transformations", R. Celenligil-Cetin, P. Paraskevopoulou, R. Dinda, R. J. Staples, E. Sinn, N. P. Rath and P. Stavropoulos, Inorganic Chemistry, 2008, 47, 1165.
."Enantiomeric Deoxycholic Acid: Total Synthesis, Characterization, and Preliminary Toxicity toward Colon Cancer Cell Lines", B. W. Katona, N. P. Rath, S. Anant, W. F. Stenson and D. F. Covey, Journal of Organic Chemistry, 2007, 72, 9298.
"Solid-State Photodimerization of 1,2-Bis(5'-pyrimidyl)ethene", E. Bosch, J. M. Matheny and N. P. Rath, Synthetic Communications 2007, 37, 3835.
"Base-promoted synthesis of monometallic and bimetallic platinum complexes containing chelating O,O- or S,S-donor ligands", N. Praingam, G. K. Anderson and N. P. Rath. Inorg. Chim. Acta, 2007, 360, 1767.
"Polymorphism in hydrazonium salt of 3,5-pyrazoledicarboxylic acid", V. S. Senthil-Kumar, T. Premkumar, S. Govindarajan, and N. P. Rath. Indian J. Chem., 2007, 46B, 141.
"h 1-vinylidene formation from internal alkynones by C-C bond migration", M. J. Shaw, S. W. Bryant and Nigam Rath. . Eur. J. Inorg. Chem., 2007, 3943.
"Metalloprobes: Synthesis, characterization, and potency of a novel gallium(III) complex in human epidermal carcinoma cells. S. E. Harpstrite", J. L. Prior, N. P. Rath and V. Sharma. J. Inorg. Biochem., 2007, 101, 1347.
"Neurosteroid analogues. Part 13: Synthetic methods for the preparation of 2b -hydroxygonane derivatives as structural mimics of ent-3a -hydroxysteroid modulators of GABAA receptors", C. Wang, N. P. Rath and D. F. Covey, Tetrahedron 2007, 63, 7977
"Dual Fluorescence from an Isonido ReIII Rhenacarborane Phosphine Complex, [7,10-m -H-7-CO-7,7-(PPh3)2-isonido-7,8,9-ReC2B7H9]", S. W. Buckner, M. J. Fischer, P. A. Jelliss, R. Luo, s. D. Minteer, N. P. Rath and A. Siemiarczuk, Inorg. Chem. 2006, 45, 7339.
"Self-Assembly of Sticky TABs: Inclusion Complexes and Hydrates from 1,3,5-Tris(4-hydroxybenzoyl)benzene", F. C. Pigge, M. K. Dighe and N. P. Rath, Cryst. Growth and Design 2006, 6, 2732.
"Steric and Electronic Effects on Arylphosphonate Elimination from Organopalladium Complexes", M. C. Kohler, R. A. Stockland and N. P. Rath Organometallics, 2006, 25, 5746.
"Concomitant Polymorphism in a Spirobicyclic Dione", V. S. S. Kumar, K. C. Sheela, V. J. Nair and N. P. Rath,Crystal Growth and Design 2004, 4, 1245.
"Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio", I. Hughes, B. Blasiole, D. Huss, M. E. Warchol, N. P. Rath, B. Hurle, E. Ignatova, J. D. Dickman, R. Thalmann, R. Levenson and D. M. Ornitz, Dev. Biol. 2004, 276, 391.
UMSL X-ray Diffraction Laboratory