Chemistry and Biochemistry

Rensheng Luo

 

Rensheng LuoDr. Luo received Ph.D. degree from the Chinese Academy of Sciences. He was a Postdoctoral Fellow at the University of Illinois at Champaign-Urbana and St Jude Children's Research Hospital prior to joining the UM-St. Louis faculty as Research Assistant Professor in the Spring of 2005 and was promoted to Research Associate Professor in 2013..

luor@umsl.edu
Office: B433
Phone: (314) 516-5330
Fax: (314) 516-5342

Research Interests

Dr. Luo's research interests involve the use of NMR techniques for generating three-dimensional structural and dynamical information on biological macromolecules, organic compounds, and organometallic complexes. NMR is being increasingly applied in chemistry, biochemistry, biology, medicine, physics and materials science. Currently, Dr. Luo is the Director of the Nuclear Magnetic Resonance Facility. Current research interests also include collaboration with scientists in solving problems on all these and related subjects using NMR spectroscopy, as well as development of techniques and implementation of new NMR experiments for users at different areas.

Selected Publications

"Distinguishing Components in Brazilian Acai (Euterpe oleraceae Mart.) and in Products Obtained in the USA by Using NMR," R. Luo, K. Tran, R. A. Levine, S. M. Nickols, D. M. Monroe, A. U. O. Sabaa-Srur and R. E. Smith, The Natural Products Journal, 2012, 2, 86.

"Proposed Benchmark Methods for Analyzing Acai (Euterpe oleraceae Mart.)," R. E. Smith, J. Eaker, K. Tran, C. Smith, D. M. Monroe, E. M. da Silva Menezes, A. U. O. Sabaa-Srur, R. Luo, W. Wycoff and W. H. Fales, The Natural Products Journal, 2012, 2,76.

"Prediction of solubility of drugs and other compounds in organic solvents.", M. H.Abraham, R. E. Smith, R. Luchtefeld,A. J. Boorem, R. Luo and W. E. Acree, Jr. J. Pharm. Sci. 201099, 1500.

"Bioavailability of apocynin through its conversion to glycoconjugate but not to diapocynin", Q. Wang, R. E. Smith, R. Luchtefeld, A. Y.Sun, A. Simonyi, R. Luo and G. Y. Sun, Phytomedicine 200815, 496 

"Synthesis of diapocynin",  M. S. Dasari, K. M. Richards, M. L. Alt, C. F. P. Crawford, A. Schleiden, J. Ingram, A. A. A. Hamidou, A. Williams, P. A. Chernovitz, R. Luo, G. Y. Sun, R.; Luchtefeld and R. E. Smith, Journal of Chemical Education2008 85,  411

"Dose Formulation and Analysis of Diapocynin", R.. Luchtefeld, R. Luo, Rensheng; K. J. Stine, M. L. Alt, P. A. Chernovitz and R. E. Smith, Journal of Agricultural and Food Chemistry2008 56,  301

"Dual Fluorescence from an Isonido ReIII Rhenacarborane Phosphine Complex, [7,10-m -H-7-CO-7,7-(PPh3)2-isonido-7,8,9-ReC2B7H9", S. W.Buckner, M. J. Fischer, P. A. Jelliss, R. Luo, S. D. Minteer, N. P. Rath and A. Siemiarczuk, Inorg. Chem.200645, 7339.

"Three-Dimensional 13C-Detected CH3-TOCSY Using Selectively Protonated Proteins: Facile Methyl Resonance Assignment and Protein Structure Determination", J. B. Jordan, H. Kovacs, Y. Wang, M. Mobli, R. Luo, C. Anklin, J. C. Hoch and R. W. Kriwacki,J. Am. Chem. Soc200628, 9119.

"Solution NMR studies of an intrinsically unstructured protein within a dilute, 75 kDa eukaryotic protein assembly; probing the practical limits for efficiently assigning polypeptide backbone resonances", Y. Wang, I. Filippov, C. Richter, R. Luo and R. W. Kriwacki, ChemBioChem2005, 6, 2242.

“Solution structure of choline binding protein A, the major adhesin of Streptococcus pneumoniae", R. Luo, B. Mann, W. S. Lewis, A. Rowe, R. Heath, M. L. Stewart, A. E. Hamburger, S. Sivakolundu, E. R. Lacy, P. J. Bjorkman, E. Tuomanen, and R. W. Kriwacki, The EMBO Journal 24, 2005, 1, 34.

“NMR assignment of the R2 domain of pneumococcal choline binding protein A (CbpA)", R. Luo, B. Mann, E. Tuomanen, and R. W. Kriwacki, J. Biomol. NMR, 2005,32(1), 93.

“Nitrate in soil humic acids revealed by nitrogen-14 nuclear magnetic resonance spectroscopy", X-A. Mao, Z. Xu, R. Luo, N. J Mathers, Y. H. Zhang, and P. G.Saffigna,Australian Journal of Soil Research, 2002, 40(5), 717.

“Raman scattering study of liquid ethylene glycol confined to nanoporous silica glasses", R. Luo, J. Jonas, J. Raman Spectr., 200132, 975.

“NMR observation of hydrolysis of acetonitrile to acetamide catalyzed by binuclear silver cryptate", R. Luo, X-A. Mao, Z-Q. Pan and Q-H. Luo, Spectrochimica Acta Part A, Mol. and Biomol Spectr. 200056, 1675.

"NMR diffusion and relaxation study on drug-protein interaction", R. Luo, M. Liu and X-A. Mao, Spectrochimica Acta Part A, Mol. and Biomol Spectr199955, 1897.