X-Ray Diffraction Laboratory
crystal structure determination is an important technique
for most inorganic and organic chemists. The X-ray Diffraction
Laboratory at UM St. Louis supports the research programs
of several research groups in the department. Also, we
collaborate with a number of groups elsewhere in the USA
and in other countries in their solid-state structure determination
research. The Laboratory is equipped with state-of-the-art
instrumentation and computational facilities for solid
state three dimensional crystal and molecular structure
determinations. The facility is located in custom-designed
laboratory space in the Center for Nanoscience, opened
in November 1996, and currently houses single crystal and
more information please contact Dr. Nigam Rath at (314)
516-5333 or by email: firstname.lastname@example.org
Crystal X-Ray Diffraction Instrumentation
Bruker APEX II Kappa Dffractometer is equipped with an
Oxford Cryostream low temperature device. Fast data collections
can be carried out using this Kappa geometry diffractometer
equipped with a 4K CCD (Charge Coupled Device) chip at
100-300K. This instrument uses a sealed tube Mo x-ray source.
Currently, most of the structure determinations are carried
out using this system.
Bruker SMART APEX II Diffractometer: This CCD (Charged Coupled Device) area detector system was updated recently to a state of the art Apex II detector equipped with a 4K CCD chip and Oxford Cryostream low temperature device for use in smal molecule crystallography. Currently this instrument is primarily used for teaching and training of students and
Post-doctoral researchers as well as for data collection by others.
A Rigaku Ultima IV Powder Diffractometer is used primarily for bulk material characterization, including air- and moisture-sensitive samples. This provides a valuable analytical tool for the identification of single and multi-component solids by comparison with known published powder patterns. It is also used to determine the homogeneity of crystalline samples from which single crystals have been used for crystal structure determination. This instrument is also capable of data collection for small angle x-ray scattering (SAXS) experiments.
Computer Facilities and Other Instrumentation
The X-ray Laboratory Computing Facility has several
workstations running crystallographic software. All
computers in the lab are integrated with the university computer
network. The Cambridge Structural Database is accessible
to all university computer system users and is hosted through
a Sun server and available on all computer lab PCs.
The sample preparation
laboratory is equipped with stereo microscopes for screening
and photographing crystals. These microscopes
are also used for crystal mounting for x-ray data collection. A
fume hood, a refrigerator and freezer for crystallization and
sample storage, together with other necessary facilities for
crystallization and crystal handling are available in the x-ray