by N.Guex & T.Schwede

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GlaxoSmithKline R&D

presents

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Deep View

Swiss-PdbViewer

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by

Nicolas Guex , Alexandre Diemand , Manuel C. Peitsch , & Torsten Schwede

News:

- Please update your preferences for the DeepView Network Service

- Deep View - spdbv version 3.7 released

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Description

Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyze several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface.

Moreover, Swiss-PdbViewer is tightly linked to Swiss-Model, an automated homology modeling server developed within the Swiss Institute of Bioinformatics (SIB) in collaboration between GlaxoSmithKline R&D and the Structural Bioinformatics Group at the Biozentrum in Basel.

Working with these two programs greatly reduces the amount of work necessary to generate models, as it is possible to thread a protein primary sequence onto a 3D template and get an immediate feedback of how well the threaded protein will be accepted by the reference structure before submitting a request to build missing loops and refine sidechain packing.

Swiss-PdbViewer can also read electron density maps, and provides various tools to build into the density.

In addition, various modeling tools are integrated and command files for popular energy minimization packages can be generated.

Finally, as a special bonus, POV-Ray scenes can be generated from the current view in order to make stunning ray-traced quality images. An example can be found here .

[last modified: 24.Mar 2003 by T.S.]